Barangay San Lorenzo belongs to the 1st congressional district of Makati and is included under Cluster 1 or Central Cluster. It is considered as one of the richest barangays in the Philippines for embraces part of the Central Business District from where its revenue mainly comes from. BSL has a total land area of 1.7341 square kilometers with a population of 10,006. The population density of Barangay San Lorenzon is computed to be 6 persons per 1,000 square meters.
Barangay San Lorenzo is considered to be predominantly commercial in land use. Prominent establishments located in the barangay are PLDT, Glorietta and Greenbelt Malls, New World Hotel, and Makati Medical Center among others.