Barangay San Isidro is one of the seven (7) barangays comprising the Westside Cluster or Cluster 2. It has a land area of 0.4829 square kilometers which is 1.8% of the City’s total land area. Based on the 2010 census of population released by the National Statistics Office, San Isidro has a percentage share of 1.4% or 7,589 versus the City’s population with a density of 16 persons per 1,000 square meters. This barangay is predominantly a residential area.
San Isidro is bounded by Barangay Palanan in the north, Pasay City and Barangay Pio del Pilar in the south, Pio del Pilar in the east, and Pasay City in the west.
Recognized structures located in the barangay includes St. Mary of the Woods School, SM Hypermarket, Fire Sub Station, Police Station Precinct 4, and Holy Family Parish Church among others.