Barangay Comembo belongs to the Makati City's second district and is located at the Southeastern of Makati and Northeastern part of Fort Bonifacio. It is part of Cluster 5 or the Eastside Cluster along with East Rembo, Pembo and Rizal.
Based on the 2010 Census of Population conducted by the National Statistics Office, Comembo has a total of 14,433 population and percentage share of 1.13% versus the city’s population with an estimate of 2,887 households. By population density on the other hand, considering its land area and population count, the barangay has 47 per 1,000 square meters. Comembo is generally a residential area except for strips of Commercial areas along the J.P. Rizal Extension, Anahaw and Sampaguita Streets.